Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26789113 | 0.99 | TIPARP (0.48) | TIPARPHSD17B10KDM4EMEN1GAA | |
| SCHEMBL25899897 | 0.88 | TIPARP (0.51) | TIPARPKDM4EL3MBTL1GRM2HDAC3 | |
| SCHEMBL25898159 | 0.85 | TIPARP (0.43) | TIPARPGRM2HDAC3HDAC1HDAC6 | |
| SCHEMBL26787748 | 0.85 | TIPARP (0.59) | TIPARPKDM4EHTTGRM2HDAC3 | |
| SCHEMBL25899977 | 0.85 | HSD17B10 (0.40) | TIPARPHSD17B10KDM4EMEN1GAA | |
| SCHEMBL25899908 | 0.84 | TIPARP (0.51) | TIPARPKDM4EL3MBTL1GRM2HDAC3 | |
| SCHEMBL25899853 | 0.84 | TIPARP (0.60) | TIPARPKDM4EHTTGRM2HDAC3 | |
| SCHEMBL25899875 | 0.84 | TIPARP (0.50) | TIPARPGRM2TNFTLR8 | |
| SCHEMBL25898391 | 0.82 | TIPARP (0.46) | TIPARPKDM4EL3MBTL1GRM2HDAC3 | |
| SCHEMBL25898542 | 0.79 | TIPARP (0.48) | TIPARPKDM4ETSHRHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |