SCHEMBL25900322

SCHEMBL25900322

C[C@@H]1[C@@H](O)[C@@H](O)[C@@H](COCCc2cn(CCOCCOCCOCCNC(=O)CCOCCOCCC(=O)Oc3c(F)c(F)c(F)c(F)c3F)nn2)O[C@H]1O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 4/20 0.39
PKM P14618 1/20 0.34
OPRM1 P35372 1/20 0.33
F2RL1 P55085 2/20 0.32
SIRT2 Q8IXJ6 1/20 0.31
FOLH1 Q04609 2/20 0.31
P2RY2 P41231 1/20 0.31
P2RY4 P51582 1/20 0.31
P2RY6 Q15077 1/20 0.31
XIAP P98170 1/20 0.30
BIRC2 Q13490 1/20 0.30
PLK1 P53350 2/20 0.30
PLK2 Q9NYY3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25496666 0.93 LGALS3 (0.37) LGALS3FOLH1
SCHEMBL25900321 0.93 LGALS3 (0.36) LGALS3FOLH1P2RY2P2RY4P2RY6
SCHEMBL25496661 0.92 LGALS3 (0.38) LGALS3PKMOPRM1F2RL1SIRT2
SCHEMBL25495211 0.90 LGALS3 (0.47) LGALS3PKMOPRM1SIRT2P2RY2
SCHEMBL25982998 0.88 LGALS3 (0.38) LGALS3PKMOPRM1F2RL1SIRT2
SCHEMBL25495188 0.86 LGALS3 (0.50) LGALS3PKMOPRM1XIAPBIRC2
SCHEMBL25495212 0.84 LGALS3 (0.41) LGALS3
SCHEMBL25495210 0.84 LGALS3 (0.47) LGALS3FOLH1P2RY2P2RY4P2RY6
SCHEMBL25496669 0.83 LGALS3 (0.46) LGALS3P2RY2P2RY4P2RY6
SCHEMBL25974686 0.82 LGALS3 (0.35) LGALS3PKMOPRM1F2RL1SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 US disclosed
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, FCGR3B, FCGR2A LGALS3 586/4885PKM 4234/4885OPRM1 2479/4885
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, ASGR1, FCGR3B LGALS3 243/4885PKM 3455/4885OPRM1 2084/4885
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A LGALS3 264/4885PKM 3998/4885OPRM1 3060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.