Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.41 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 6/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963283 | 0.90 | CYP2D6 (0.43) | CYP1A2POLBCYP3A4CYP2C19PIK3CD | |
| SCHEMBL25900234 | 0.85 | PGR (0.51) | IP6K1IP6K3IP6K2PGRAKR1B1 | |
| SCHEMBL25900036 | 0.85 | ADRA2B (0.48) | PIK3CDCYP2D6IP6K1IP6K3IP6K2 | |
| SCHEMBL6639261 | 0.84 | PIK3CD (0.46) | CYP1A2POLBCYP3A4CYP2C19PIK3CD | |
| SCHEMBL26021842 | 0.84 | CYP2D6 (0.40) | PIK3CDCYP2D6IP6K1IP6K3IP6K2 | |
| SCHEMBL22271441 | 0.83 | CYP1A2 (0.63) | CYP1A2POLBCYP3A4CYP2C19PGR | |
| Hydrochloric Acid SCHEMBL6634275 | 0.83 | PIK3CD (0.45) | CYP1A2POLBCYP3A4CYP2C19PIK3CD | |
| SCHEMBL25900304 | 0.83 | CYP2D6 (0.39) | PIK3CDCYP2D6IP6K1IP6K3IP6K2 | |
| SCHEMBL25900356 | 0.82 | PGR (0.52) | POLBPIK3CDCYP2D6IP6K1IP6K3 | |
| SCHEMBL25900619 | 0.82 | PGR (0.39) | PIK3CDCYP2D6IP6K1IP6K3IP6K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |