Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31561370 | 1.00 | SLC6A3 (0.31) | SLC6A3KCNH2TAAR1CHEK1ELANE | |
| SCHEMBL25317695 | 0.83 | CTSC (0.33) | — | |
| SCHEMBL31140836 | 0.83 | CTSC (0.33) | — | |
| SCHEMBL25316393 | 0.81 | CHRNB2 (0.31) | — | |
| SCHEMBL26496339 | 0.75 | CTSC (0.32) | — | |
| SCHEMBL31140819 | 0.74 | MAOB (0.35) | — | |
| SCHEMBL25317458 | 0.74 | MAOB (0.35) | — | |
| SCHEMBL31561368 | 0.73 | MAPK1 (0.40) | — | |
| SCHEMBL31140832 | 0.73 | MAPK1 (0.40) | — | |
| SCHEMBL25901441 | 0.73 | MAPK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139534-A1 | SPIROCYCLIC PIPERIDINYL DERIVATIVES AS COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2023-07-27 | — | — | WO | disclosed |