Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERF2 | Q15554 | 4/20 | 0.48 |
| ▸ | GHSR | Q92847 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21430295 | 0.82 | TERF2 (0.47) | TERF2GHSRHDAC4HDAC3HDAC1 | |
| SCHEMBL30576705 | 0.81 | HDAC3 (0.49) | HDAC4HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL21430287 | 0.81 | HDAC3 (0.48) | GHSRHDAC4HDAC3HDAC1HDAC2 | |
| SCHEMBL22928930 | 0.81 | HDAC3 (0.48) | GHSRHDAC4HDAC3HDAC1HDAC2 | |
| Cyclomontanin D SCHEMBL30139332 | 0.80 | SLC6A3 (0.54) | TERF2HDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL29412929 | 0.78 | HDAC4 (0.54) | GHSRHDAC4 | |
| SCHEMBL21430233 | 0.78 | TERF2 (0.41) | TERF2GHSRHDAC4HDAC3HDAC1 | |
| SCHEMBL22929005 | 0.78 | TERF2 (0.41) | TERF2GHSRHDAC4HDAC3HDAC1 | |
| SCHEMBL1519049 | 0.77 | ITGAV (0.47) | TERF2GHSRHDAC4NTSR1 | |
| SCHEMBL29352662 | 0.76 | HDAC8 (0.49) | HDAC4HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713339-B2 | Macrocyclization of peptidomimetics | UNIVERSITY OF WARWICK (GB) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713339-B2 | Macrocyclization of peptidomimetics | NGLY1, MAX, PTMA | TERF2 1137/4885GHSR 190/4885HDAC4 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.