SCHEMBL259018

SCHEMBL259018

O=C(O)COCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
EPHX2 P34913 1/20 0.46
CASP3 P42574 2/20 0.44
FABP7 O15540 2/20 0.43
FABP5 Q01469 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511484 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL29409577 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31749859 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31355501 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL178765 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL4557019 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL1593608 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL4557247 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31309927 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL29634951 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106749613-B Synthetic method of somaglutide 江苏诺泰澳赛诺生物制药股份有限公司 2020-08-18 CN claimed
US-20190352625-A1 MUTANTS OF COCAINE ESTERASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2019-11-21 US claimed
US-10160960-B2 Mutants of cocaine esterase THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2018-12-25 US claimed
US-20180057558-A1 Synthesis of GLP-1 Peptides NOVETIDE, LTD. (IL) 2018-03-01 US claimed
EP-3221342-A1 SYNTHESIS OF GLP-1 PEPTIDES Novetide Ltd. (IL) 2017-09-27 EP claimed
US-20160177277-A1 MUTANTS OF COCAINE ESTERASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-06-23 US claimed
WO-2016046753-A1 SYNTHESIS OF GLP-1 PEPTIDES NOVETIDE, LTD. (IL) 2016-03-31 WO claimed
EP-2111237-B1 FIBRIN-BINDING PEPTIDES AND CONJUGATES THEREOF BRACCO IMAGING SPA (IT) 2015-03-18 EP claimed
WO-2015021187-A1 MUTANTS OF COCAINE ESTERASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2015-02-12 WO claimed
US-20140134197-A1 Mimotopic Peptides for the Diagnosis and Treatment of Multiple sclerosis Calenoff, Emanuel (US) 2014-05-15 US claimed
US-20080267988-A1 Myelin specific IgE unencumbered by corresponding blocking antibodies as a causative factor in multiple sclerosis ENTERON LIMITED PARTNERSHIP (US) 2008-10-30 US claimed
WO-2008127642-A1 MYELIN SPECIFIC IGE UNENCUMBERED BY CORRESPONDING BLOCKING ANTIBODIES AS A CAUSATIVE FACTOR IN MULTIPLE SCLEROSIS ENTERON LIMITED PARTNERSHIP (US) 2008-10-23 WO claimed
US-20260132182-A1 CO-AGONISTS OF THE GLP-1 AND AMYLIN RECEPTORS NOVO NORDISK AS (DK) 2026-05-14 US disclosed
EP-4740955-A2 NOVEL GLP-1 ANALOGUES Sun Pharmaceutical Industries Limited (IN) 2026-05-13 EP disclosed
US-20260125445-A1 GLP-1 DERIVATIVES AND USES THEREOF NOVO NORDISK AS (DK) 2026-05-07 US disclosed
EP-4731257-A1 CONJUGATES OF SAPONIN AND ANTISENSE OLIGONUCLEOTIDES FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Sapreme Technologies B.V. (NL) 2026-04-29 EP disclosed
WO-1999037670-A1 SYNTHETIC POLYMERS AND METHODS, KITS OR COMPOSITIONS FOR MODULATING THE SOLUBILITY OF SAME BOSTON PROBES, INC. (US) 1999-07-29 WO disclosed
WO-1999022018-A2 METHODS, KITS AND COMPOSITIONS PERTAINING TO PNA MOLECULAR BEACONS BOSTON PROBES, INC. (US) 1999-05-06 WO disclosed
WO-1999021881-A1 METHODS, KITS AND COMPOSITIONS PERTAINING TO LINEAR BEACONS BOSTON PROBES, INC. (US) 1999-05-06 WO disclosed
WO-1998024933-A1 METHODS, KITS AND COMPOSITIONS FOR SUPPRESSING THE BINDING OF DETECTABLE PROBES TO NON-TARGET SEQUENCES IN HYBRIDIZATION ASSAYS BOSTON PROBES, INC. (US) 1998-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057558-A1 Synthesis of GLP-1 Peptides GLP1R, GIPR, IAPP KMT2A 2774/4885SMN1; SMN2 4062/4885LMNA 3319/4885
US-20260132182-A1 CO-AGONISTS OF THE GLP-1 AND AMYLIN RECEPTORS GLP1R, GCGR, GIPR KMT2A 2360/4885SMN1; SMN2 3048/4885LMNA 3349/4885
US-20260125445-A1 GLP-1 DERIVATIVES AND USES THEREOF GLP1R, GIPR, ARRB1 KMT2A 2440/4885SMN1; SMN2 3963/4885LMNA 2760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.