SCHEMBL4557019

SCHEMBL4557019

O=C(O)COCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
EPHX2 P34913 1/20 0.46
CASP3 P42574 2/20 0.44
FABP7 O15540 2/20 0.43
FABP5 Q01469 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511484 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL29409577 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31749859 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31355501 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL178765 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL259018 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL1593608 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL4557247 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31309927 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL29634951 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216526-A1 PREPARATION METHOD FOR DUAL-DRUG-LINKER OF ADC AND USE THEREOF CHENGDU SCIMOUNT PHARMATECH CO., LTD. (CN) 2024-07-04 US disclosed
US-7598421-B2 Materials for the delivery of biologically-active material to cells UCL BIOMEDICA PLC (GB) 2009-10-06 US disclosed
US-7598421-B2 Materials for the delivery of biologically-active material to cells UCL BIOMEDICA PLC (GB) 2009-10-06 US disclosed
US-7598421-B2 Materials for the delivery of biologically-active material to cells UCL BIOMEDICA PLC (GB) 2009-10-06 US disclosed
US-20050245446-A1 Materials for the delivery of biologically-active material to cells NANOGENICS LIMITED (GB) 2005-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245446-A1 Materials for the delivery of biologically-active material to cells ITGB1, ITGA2B, ITGB2 KMT2A 4254/4885SMN1; SMN2 2326/4885LMNA 105/4885
US-20240216526-A1 PREPARATION METHOD FOR DUAL-DRUG-LINKER OF ADC AND USE THEREOF SKP1, ADCY7, ERBB2 KMT2A 1387/4885SMN1; SMN2 1784/4885LMNA 1812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.