SCHEMBL178765

SCHEMBL178765

O=C(O)COCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
EPHX2 P34913 1/20 0.46
CASP3 P42574 2/20 0.44
FABP7 O15540 2/20 0.43
FABP5 Q01469 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511484 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL29409577 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31749859 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31355501 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL259018 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL4557019 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL1593608 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL4557247 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31309927 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL29634951 1.00 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250049904-A1 IMMUNOSTIMULATORY COMPOSITIONS MALCORP BIODISCOVERIES LIMITED (NZ) 2025-02-13 US disclosed
CN-117736151-A Ligand compound of E3 ubiquitin ligase CDC20 and application thereof 南京奥瑞药业有限公司 2024-03-22 CN disclosed
WO-2023121483-A1 IMMUNOSTIMULATORY COMPOSITIONS VICTORIA LINK LIMITED (NZ) 2023-06-29 WO disclosed
US-10864279-B2 Linker-drug and antibody-drug conjugate (ADC) employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2020-12-15 US disclosed
US-20180169262-A1 LINKER-DRUG AND ANTIBODY-DRUG CONJUGATE (ADC) EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-06-21 US disclosed
US-20180169262-A1 LINKER-DRUG AND ANTIBODY-DRUG CONJUGATE (ADC) EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-06-21 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-8445450-B2 Antithrombotic dual inhibitors comprising a biotin residue MERCK SHARP & DOHME B.V. (NL) 2013-05-21 US disclosed
US-8445450-B2 Antithrombotic dual inhibitors comprising a biotin residue MERCK SHARP & DOHME B.V. (NL) 2013-05-21 US disclosed
US-20120245109-A1 ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN RESIDUE MSD OSS B.V. (NL) 2012-09-27 US disclosed
US-8168595-B2 Antithrombotic dual inhibitors comprising a biotin residue Msd Oss B.V (NL) 2012-05-01 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
EP-1830887-B1 ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN RESIDUE ORGANON NV (NL) 2011-03-09 EP disclosed
EP-1830887-B1 ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN RESIDUE ORGANON NV (NL) 2011-03-09 EP disclosed
EP-1991271-B1 ANTICOAGULANT ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN LABEL ORGANON NV (NL) 2011-03-09 EP disclosed
EP-1991271-B1 ANTICOAGULANT ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN LABEL ORGANON NV (NL) 2011-03-09 EP disclosed
US-20100029582-A1 Anticoagulant Antithrombotic Dual Inhibitors Comprising a Biotin Label MERCK SHARP & DOHME B.V. (NL) 2010-02-04 US disclosed
US-20100004186-A1 Antithrombotic Dual Inhibitors Comprising A Biotin Residue N.V. ORGANON (NL) 2010-01-07 US disclosed
WO-2007042469-A2 ANTICOAGULANT ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN LABEL N.V. ORGANON (NL) 2007-04-19 WO disclosed
WO-2006067173-A2 ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN RESIDUE N.V. ORGANON (NL) 2006-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029582-A1 Anticoagulant Antithrombotic Dual Inhibitors Comprising a Biotin Label FGB, F13B, SERPINC1 KMT2A 1936/4885SMN1; SMN2 4855/4885LMNA 328/4885
US-20100004186-A1 Antithrombotic Dual Inhibitors Comprising A Biotin Residue SERPINC1, BRS3, TBXA2R KMT2A 4368/4885SMN1; SMN2 3923/4885LMNA 1485/4885
US-20250049904-A1 IMMUNOSTIMULATORY COMPOSITIONS CD69, PBK, GALK1 KMT2A 1159/4885SMN1; SMN2 1866/4885LMNA 2182/4885
US-20180169262-A1 LINKER-DRUG AND ANTIBODY-DRUG CONJUGATE (ADC) EMPLOYING THE SAME ADCY7, ADCY1, ADCY9 KMT2A 1373/4885SMN1; SMN2 2854/4885LMNA 1496/4885
US-20120245109-A1 ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN RESIDUE TBXA2R, MC3R, BRS3 KMT2A 4322/4885SMN1; SMN2 3851/4885LMNA 1800/4885
US-10864279-B2 Linker-drug and antibody-drug conjugate (ADC) employing the same ADCY7, ADCY1, ADCY9 KMT2A 1373/4885SMN1; SMN2 2854/4885LMNA 1496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.