Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120887 | 0.84 | POLRMT (0.53) | POLRMTP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL22646504 | 0.84 | POLRMT (0.51) | POLRMTP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL23711110 | 0.84 | POLRMT (0.51) | POLRMTP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL21343890 | 0.83 | POLRMT (0.52) | POLRMTP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL15998230 | 0.82 | POLRMT (0.50) | POLRMTP2RX1P2RX3P2RX2P2RX4 | |
| Rdv-Tp SCHEMBL23278555 | 0.82 | POLRMT (0.51) | POLRMTP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL10120078 | 0.82 | POLRMT (0.51) | POLRMTP2RX1P2RX3P2RX2P2RX4 | |
| Rdv-Tp SCHEMBL24492746 | 0.82 | POLRMT (0.51) | POLRMTP2RX1P2RX3P2RX2P2RX4 | |
| Rdv-Tp SCHEMBL24492745 | 0.82 | POLRMT (0.51) | POLRMTP2RX1P2RX3P2RX2P2RX4 | |
| Rdv-Tp SCHEMBL10120881 | 0.82 | POLRMT (0.51) | POLRMTP2RX1P2RX3P2RX2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248753-A1 | PHOSPHOLIPID COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-08-10 | — | — | US | disclosed |
| US-20230233587-A1 | REMDESIVIR TREATMENT METHODS | GILEAD SCIENCES, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233587-A1 | REMDESIVIR TREATMENT METHODS | EIF2AK2, MTAP, ACE | POLRMT 44/4885P2RX1 2072/4885P2RX3 2485/4885 |
| US-20230248753-A1 | PHOSPHOLIPID COMPOUNDS AND USES THEREOF | PHOSPHO1, SGMS2, SGMS1 | POLRMT 361/4885P2RX1 1404/4885P2RX3 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.