Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30675380 | 0.80 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL20974733 | 0.80 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL2578619 | 0.79 | NAAA (0.38) | NAAA | |
| SCHEMBL4516522 | 0.78 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL4516524 | 0.78 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL27006664 | 0.76 | SMYD2 (0.38) | SMYD2PSMB5CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL29246124 | 0.75 | SMYD2 (0.35) | SMYD2RIPK1 | |
| SCHEMBL20974903 | 0.75 | SMYD2 (0.35) | SMYD2RIPK1 | |
| SCHEMBL29246122 | 0.75 | SMYD2 (0.35) | SMYD2RIPK1 | |
| SCHEMBL27006658 | 0.75 | SMYD2 (0.38) | SMYD2PSMB5CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |