SCHEMBL25903808

SCHEMBL25903808

N#Cc1ccc(-c2nc(-c3ccccc3)cc(-c3ccccc3)n2)cc1-n1c2ccccc2c2c1ccc1c3ccccc3n(-c3ccccc3)c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 1/20 0.35
ALDH1A1 P00352 5/20 0.33
HPGD P15428 3/20 0.33
MAPK1 P28482 3/20 0.33
MAPT P10636 2/20 0.33
ALOX15 P16050 1/20 0.33
MCL1 Q07820 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CHEK1 O14757 2/20 0.32
KCNH2 Q12809 2/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
SQOR Q9Y6N5 3/20 0.32
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CSNK2A1 P68400 1/20 0.31
MEN1 O00255 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25903485 0.95 KDM4E (0.35) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL25902628 0.94 KDM4E (0.36) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL19685072 0.90 ALDH1A1 (0.33) KDM4EALDH1A1HPGDMAPK1MAPT
SCHEMBL25902624 0.90 ALDH1A1 (0.36) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL19685075 0.89 KDM4E (0.35) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL25903493 0.88 KDM4E (0.36) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL25903072 0.88 KDM4E (0.36) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL27016190 0.87 NR3C1 (0.33) KDM4EL3MBTL1ATM
SCHEMBL25903087 0.87 KDM4E (0.35) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL23262664 0.87 KDM4E (0.34) KDM4EL3MBTL1ATMALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023140706-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 WO disclosed