Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 8/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25903699 | 0.83 | PDE3B (0.55) | WEE1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL25904763 | 0.80 | MEN1 (0.58) | FLT3PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL25904145 | 0.77 | CNR1 (0.40) | PDE3BPDE3AMEN1KMT2ARXFP1 | |
| SCHEMBL25903697 | 0.77 | PDE3B (0.56) | MAP2CHEK1WEE1PDE3BPDE3A | |
| SCHEMBL25904272 | 0.75 | F11 (0.45) | MAP2CHEK1WEE1PDE3BPDE3A | |
| SCHEMBL25905129 | 0.74 | TNKS2 (0.41) | CHEK1WEE1PDE3BPDE3AMEN1 | |
| SCHEMBL25905198 | 0.74 | PDE3B (0.41) | PDE3BPDE3AMEN1KMT2ARXFP1 | |
| SCHEMBL10378102 | 0.71 | PDE3B (0.68) | PDE3BPDE3A | |
| SCHEMBL25904123 | 0.70 | KDM4E (0.38) | PDE3BPDE3AMEN1KMT2ARXFP1 | |
| SCHEMBL32659853 | 0.70 | PDE3B (0.57) | PDE3BPDE3ARHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147513-A2 | COMPOSITIONS OF AUTOPHAGY MODULATING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2023-08-03 | — | — | WO | disclosed |