Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317219 | 0.86 | AOC3 (0.60) | AOC3HRH3CA1CA2CA9 | |
| SCHEMBL26029591 | 0.85 | AOC3 (0.54) | AOC3HRH3MEN1MAPTKMT2A | |
| SCHEMBL25315042 | 0.84 | AOC3 (0.53) | AOC3HRH3CA1CA2CA7 | |
| SCHEMBL22713834 | 0.81 | AOC3 (0.53) | AOC3CA1CA2CA7CA9 | |
| SCHEMBL29798486 | 0.81 | AOC3 (0.53) | AOC3CA1CA2CA7CA9 | |
| SCHEMBL30485952 | 0.75 | AOC3 (0.44) | AOC3CA1CA2 | |
| SCHEMBL25903936 | 0.74 | HRH3 (0.44) | HRH3MEN1NPC1ALDH1A1GAA | |
| SCHEMBL22725851 | 0.73 | AOC3 (1.00) | AOC3 | |
| SCHEMBL22725850 | 0.73 | AOC3 (1.00) | AOC3 | |
| SCHEMBL25910299 | 0.72 | GPR119 (0.52) | CA1CA2CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |