Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA7 | P43166 | 4/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25903923 | 0.84 | GPR119 (0.49) | GPR119CA1CA2CA9MAPK1 | |
| SCHEMBL19865381 | 0.79 | RYR2 (0.56) | GPR119CA1CA2CA9CA5A | |
| SCHEMBL25904287 | 0.77 | MAPK1 (0.44) | CA1CA2CA9CA7CA14 | |
| SCHEMBL26022348 | 0.76 | GPR119 (0.43) | GPR119MAPK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL26029593 | 0.74 | HRH3 (0.42) | CA1CA2CA9CA7CA14 | |
| SCHEMBL10071533 | 0.73 | HRH3 (0.51) | CA1CA2CA9CA7CA12 | |
| SCHEMBL25904264 | 0.72 | AOC3 (0.57) | GPR119CA1CA2CA9CA7 | |
| SCHEMBL25903936 | 0.71 | HRH3 (0.44) | GPR119MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL23222346 | 0.70 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTKDM4ETSHRALDH1A1 | |
| SCHEMBL11444799 | 0.70 | TSHR (0.56) | MAPK1SMN1; SMN2MAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |