SCHEMBL259056

SCHEMBL259056

O=C(OCC1CCC2OC2C1)c1ccc(C(=O)OCC2CCC3OC3C2)cc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
PPM1B O75688 2/20 0.42
CARM1 Q86X55 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
CHRNB2 P17787 4/20 0.41
CHRNA4 P43681 4/20 0.41
CHRNA7 P36544 3/20 0.41
CHRNA5 P30532 2/20 0.41
UPP1 Q16831 1/20 0.40
JMJD6 Q6NYC1 1/20 0.40
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28193768 0.94 DRD2 (0.43) DRD2DRD4PPM1BCARM1PRMT6
SCHEMBL13935565 0.91 KDM4E (0.42) DRD2DRD4PPM1BCARM1PRMT6
SCHEMBL14154791 0.89 DRD2 (0.38) DRD2DRD4PPM1BCARM1PRMT6
SCHEMBL28973816 0.88 JMJD6 (0.40) DRD2DRD4PPM1BCHRNB2CHRNA4
SCHEMBL17482312 0.86 PPM1B (0.39) DRD2DRD4PPM1BCARM1PRMT6
SCHEMBL11494480 0.85 CHRNB4 (0.43) CHRNB2CHRNA4NPC1CHRNB4CHRNA3
SCHEMBL29690854 0.85 CHRNB4 (0.43) CHRNB2CHRNA4NPC1CHRNB4CHRNA3
SCHEMBL14163687 0.81 JMJD6 (0.38) DRD2DRD4PPM1BCARM1PRMT6
SCHEMBL14411024 0.81 MAPT (0.37) DRD2DRD4PPM1BCARM1PRMT6
SCHEMBL17012024 0.80 PPM1B (0.35) PPM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5176780-A Oxazine Resin Adhesives GURIT-ESSEX AG (CH) 1993-01-05 US claimed
EP-0178414-B1 CHEMICALLY CURABLE RESINS DERIVED FROM 1-OXA-3-AZA-TETRALIN GROUPS CONTAINING COMPOUNDS AND CYCLOALIPHATIC EPOXY RESINS, PROCESS FOR THEIR PREPARATION AND CURE AS WELL AS THE USE OF SUCH RESINS Gurit-Essex AG (CH) 1988-01-13 EP claimed
US-20230025661-A1 Amine-Substituted 2-Amino-Ethan-1-Olyl Polymers, Polyimides, Articles, and Methods ESSEX FURUKAWA MAGNET WIRE USA LLC 2023-01-26 US disclosed
US-10133174-B2 Liquid photoreactive composition and method of fabricating structures 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-11-20 US disclosed
EP-3077421-B1 LIQUID PHOTOREACTIVE COMPOSITION AND METHOD OF FABRICATING STRUCTURES 3M INNOVATIVE PROPERTIES CO (US) 2018-01-31 EP disclosed
US-20160306277-A1 LIQUID PHOTOREACTIVE COMPOSITION AND METHOD OF FABRICATING STRUCTURES 3M INNOVATIVE PROPERTIES COMPANY 2016-10-20 US disclosed
EP-3077421-A2 LIQUID PHOTOREACTIVE COMPOSITION AND METHOD OF FABRICATING STRUCTURES 3M Innovative Properties Company (US) 2016-10-12 EP disclosed
US-8132494-B1 Ballistic resistant composite article having improved matrix system HONEYWELL INTERNATIONAL, INC. (US) 2012-03-13 US disclosed
US-20090041945-A1 ACTIVE RAY CURABLE COMPOSITION, POLYMERIZATION METHOD, ACTIVE RAY CURABLE INK, IMAGE FORMING METHOD, AND INK-JET RECORDING APPARATUS KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-02-12 US disclosed
US-7390840-B2 Active ray curable composition, active ray curable ink, image forming method and inkjet recording apparatus utilizing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-24 US disclosed
EP-1840148-A1 POLYMERIZABLE ACTINIC RADIATION CURABLE COMPOSITION, POLYMERIZATION METHOD, ACTINIC RADIATION CURABLE INK AND IMAGE FORMATION METHOD, AND INK JET RECORDING APPARATUS AND EPOXY COMPOUND Konica Minolta Medical & Graphic, Inc. (JP) 2007-10-03 EP disclosed
WO-1992010363-A1 FLAME RESISTANT BALLISTIC COMPOSITE ALLIED-SIGNAL INC. (US) 1992-06-25 WO disclosed
WO-1991012136-A1 ROLE OF MOLDED, BALLISTIC RESISTANT CLOTH AND METHOD OF MAKING SAME ALLIED-SIGNAL INC. (US) 1991-08-22 WO disclosed
US-4845162-A CLEAR, WINDOWS, WINDSHIELDS, MOLDING MATERIALS ALLIED-SIGNAL INC. (US) 1989-07-04 US disclosed
US-4277583-A POLYEPOXIDES OF IMPROVED WORKABILITY AND HEAT RESISTANCE PLASTICS ENGINEERING COMPANY (US) 1981-07-07 US disclosed
US-4241661-A BY COATING WITH AN ANTIOXIDANT TO DECREASE OXIDATIVE HARDENING HERCULES INCORPORATED (US) 1980-12-30 US disclosed
US-3984265-A CARBOXY TERMINATED POLYBUTADIENE AS BINDER HERCULES INCORPORATED (US) 1976-10-05 US disclosed
US-3982975-A UNCURED CARBOXYLATED RUBBER, EPOXIDE CURING AGENT, PHENYLENEDIAMINE ANTIOXIDANT HERCULES INCORPORATED (US) 1976-09-28 US disclosed
US-3957716-A Sized carbon fibers HERCULES INCORPORATED (US) 1976-05-18 US disclosed
US-3948698-A CATALYST OF AN ALIPHATIC ACID CHROMIUM SALT, CHROMIUM NAPHTHENATE OR VANADIUM NAPHTHENATE HERCULES INCORPORATED (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090041945-A1 ACTIVE RAY CURABLE COMPOSITION, POLYMERIZATION METHOD, ACTIVE RAY CURABLE INK, IMAGE FORMING METHOD, AND INK-JET RECORDING APPARATUS RIF1, NAP1L4, NAP1L1 DRD2 3655/4885DRD4 3628/4885PPM1B 991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.