SCHEMBL14411024

SCHEMBL14411024

CC(CCC1OC1C)COC(=O)c1ccc(C(=O)OCC2CCC3OC3C2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
NPC1 O15118 2/20 0.35
CARM1 Q86X55 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
PPM1B O75688 2/20 0.34
JMJD6 Q6NYC1 1/20 0.34
CHRNB2 P17787 3/20 0.33
CHRNA7 P36544 3/20 0.33
CHRNA4 P43681 3/20 0.33
CHRNA5 P30532 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HTT P42858 2/20 0.33
RAB9A P51151 1/20 0.33
POLB P06746 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
UPP1 Q16831 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14394511 0.85
SCHEMBL259056 0.81 DRD2 (0.44) NPC1CARM1PRMT6PPM1BJMJD6
SCHEMBL9974593 0.80
SCHEMBL12787230 0.77 GPR88 (0.30)
SCHEMBL13901203 0.77 L3MBTL1 (0.32)
SCHEMBL17482312 0.76 PPM1B (0.39) MAPTNPC1CARM1PRMT6PPM1B
SCHEMBL28193768 0.76 DRD2 (0.43) MAPTNPC1CARM1PRMT6PPM1B
SCHEMBL10062350 0.74 PPM1B (0.31) PPM1B
SCHEMBL13935565 0.73 KDM4E (0.42) NPC1CARM1PRMT6PPM1BJMJD6
SCHEMBL14154791 0.72 DRD2 (0.38) CARM1PRMT6PPM1BJMJD6CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1837357-A1 ACTINIC RAY CURABLE COMPOSITION, ACTINIC RAY CURABLE INK, METHOD OF IMAGE FORMING THEREWITH, INKJET RECORDING APPARATUS AND EPOXY COMPOUND Konica Minolta Medical & Graphic, Inc. (JP) 2007-09-26 EP disclosed