Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 4/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669362 | 0.83 | PDE4D (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6671515 | 0.83 | PDE4D (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9074021 | 0.83 | PDE4D (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9074022 | 0.83 | PDE4D (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6671511 | 0.83 | PDE4D (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL23867782 | 0.82 | BCHE (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21374478 | 0.80 | PDE4D (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6671627 | 0.80 | BCHE (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL18580339 | 0.79 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL18580338 | 0.79 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3839008-B1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-07-26 | — | — | EP | disclosed |