Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | MERTK | Q12866 | 3/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 2/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965651 | 0.90 | BCHE (0.48) | BCHEALDH1A1METAP2 | |
| SCHEMBL23867726 | 0.90 | BCHE (0.47) | BCHEALDH1A1METAP2MERTKAXL | |
| SCHEMBL25906367 | 0.80 | PSEN1 (0.42) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8425927 | 0.79 | ALDH1A1 (0.50) | BCHEALDH1A1 | |
| SCHEMBL404401 | 0.79 | BCHE (0.49) | BCHEALDH1A1METAP2KLK7KLK5 | |
| SCHEMBL402725 | 0.79 | BCHE (0.46) | BCHEALDH1A1KLK7KLK5 | |
| SCHEMBL14478921 | 0.79 | BCHE (0.49) | BCHEALDH1A1METAP2KLK7KLK5 | |
| SCHEMBL14362993 | 0.79 | BCHE (0.49) | BCHEALDH1A1METAP2KLK7KLK5 | |
| SCHEMBL19976411 | 0.79 | BCHE (0.46) | BCHEALDH1A1KLK7KLK5 | |
| SCHEMBL22236634 | 0.78 | BCHE (0.48) | BCHEALDH1A1METAP2PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237884-B1 | PROCESS FOR THE PREPARATION OF TRANS-3-ALKYLOXY-4-HYDROXYTETRAHYDROFURAN | EASTMAN CHEM CO (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6140516-A | Process for the preparation of trans-3-alkyloxy-4-hydroxytetrahydrofuran | EASTMAN CHEMICAL COMPANY (US) | 2000-10-31 | — | — | US | disclosed |