SCHEMBL25906375

SCHEMBL25906375

CC(CI)C1CCC(=O)NC1=O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 18/20 0.40
DDB1 Q16531 14/20 0.40
POLB P06746 1/20 0.39
ALDH1A1 P00352 1/20 0.37
CHRM2 P08172 1/20 0.37
OPRM1 P35372 1/20 0.37
IKZF3 Q9UKT9 1/20 0.37
CYP1A2 P05177 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TNF P01375 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435687 0.85 CRBN (0.40) CRBNDDB1POLB
SCHEMBL22623767 0.80 CRBN (0.44) CRBNDDB1POLBALDH1A1CHRM2
SCHEMBL10073932 0.80 CRBN (0.44) CRBNDDB1POLBALDH1A1CHRM2
SCHEMBL25046231 0.80 CRBN (0.44) CRBNDDB1POLBALDH1A1CHRM2
Hydrochloric Acid SCHEMBL2111827 0.76 CRBN (0.41) CRBNDDB1POLBALDH1A1CHRM2
SCHEMBL25863629 0.74 CRBN (0.43) CRBNDDB1POLB
SCHEMBL24315849 0.69 CRBN (0.41) CRBNDDB1POLB
SCHEMBL11855537 0.69 CRBN (0.50) CRBNDDB1POLBALDH1A1CHRM2
SCHEMBL26274093 0.69 CRBN (0.43) CRBNDDB1POLBALDH1A1
SCHEMBL26955412 0.68 CRBN (0.43) CRBNDDB1POLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230236502-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2023-07-27 US disclosed