SCHEMBL25907165

SCHEMBL25907165

C=C(CC=N)NC1CC(C)(O)C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25907261 0.67 — —
SCHEMBL18214762 0.62 ATM (0.42) —
SCHEMBL14809937 0.62 POLB (0.36) GAA
SCHEMBL17461457 0.62 POLB (0.36) GAA
SCHEMBL18987902 0.62 POLB (0.36) GAA
SCHEMBL11896737 0.62 — —
SCHEMBL20464452 0.62 MTNR1A (0.40) GAA
SCHEMBL25952839 0.62 MTNR1A (0.40) GAA
SCHEMBL25332801 0.60 MTNR1A (0.39) GAA
SCHEMBL25948458 0.60 MTNR1A (0.39) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141432-A2 APOL1 INHIBITORS AND METHODS OF USE MAZE THERAPEUTICS, INC. (US) 2023-07-27 — — WO disclosed
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