SCHEMBL25907202

SCHEMBL25907202

C[C@@H](I)CC1=Cc2cc(Cl)ccc2C1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.40
DRD4 P21917 4/20 0.40
DRD3 P35462 1/20 0.33
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 1/20 0.33
PNMT P11086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5953680 0.78 DRD2 (0.41) DRD2DRD4DRD3HTR2AHTR2C
SCHEMBL5953999 0.76 DRD2 (0.40) DRD2DRD4DRD3HTR2AHTR2C
SCHEMBL5954085 0.73 DRD2 (0.38) DRD2DRD4DRD3HTR2AHTR2C
SCHEMBL16544545 0.71 DRD2 (0.43) DRD2DRD4DRD3HTR2AHTR2C
SCHEMBL28752259 0.70 DRD2 (0.39) DRD2DRD4DRD3HTR2AHTR2C
SCHEMBL5954069 0.69 DRD2 (0.48) DRD2DRD4DRD3HTR2AHTR2C
SCHEMBL5954094 0.65 DRD2 (0.41) DRD2DRD4DRD3HTR2AHTR2C
SCHEMBL5953678 0.65 MCHR1 (0.33) DRD2DRD4HTR2AHTR2CHTR2B
SCHEMBL11435874 0.63 DRD2 (0.36) DRD2DRD4HTR2AHTR2CHTR2B
SCHEMBL21694413 0.62 ACHE (0.49) DRD3HTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134696-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE 华为技术有限公司 2023-07-20 WO disclosed