Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.55 |
| ▸ | HTR2A | P28223 | 5/20 | 0.50 |
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029922 | 0.86 | HTR1A (0.67) | HTR1AHTR2AHTR2CHTR2BMPO | |
| SCHEMBL27189556 | 0.83 | HTR1A (0.54) | HTR1AHTR2AHTR2CHTR2BMPO | |
| SCHEMBL24420538 | 0.79 | HTR1A (0.69) | HTR1AHTR2AHTR2CHTR2BMPO | |
| SCHEMBL25029941 | 0.79 | HTR1A (0.48) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL4401430 | 0.75 | HTR1A (0.78) | HTR1AHTR2AHTR2CHTR2BMPO | |
| SCHEMBL25028300 | 0.75 | HTR1A (0.53) | HTR1AHTR2AHTR2CHTR2BMPO | |
| SCHEMBL24420553 | 0.72 | HTR1A (0.59) | HTR1AHTR2AHTR2CHTR2BMPO | |
| SCHEMBL25747524 | 0.71 | HTR1A (1.00) | HTR1AHTR2AHTR2CHTR2BMPO | |
| SCHEMBL30483767 | 0.70 | GPR84 (0.63) | HTR1AHTR2AHTR2CHTR2BMPO | |
| SCHEMBL25747528 | 0.70 | GPR84 (0.63) | HTR1AHTR2AHTR2CHTR2BMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4230195-A1 | COMPOSITIONS AND METHODS OF USE COMPRISING SUBSTANCES WITH NEURAL PLASTICITY ACTIONS ADMINISTERED AT NON-PSYCHEDELIC / PSYCHOTOMIMETIC DOSAGES AND FORMULATIONS | Arbormentis LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-4219490-A1 | COMPOSITIONS AND METHODS OF USE COMPRISING SUBSTANCES WITH NEURAL PLASTICITY ACTIONS ADMINISTERED AT NON-PSYCHEDELIC / PSYCHOTOMIMETIC DOSAGES AND FORMULATIONS | Arbormentis LLC (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-4219498-A1 | COMPOSITIONS AND METHODS OF USE COMPRISING SUBSTANCES WITH NEURAL PLASTICITY ACTIONS ADMINISTERED AT NON-PSYCHEDELIC / PSYCHOTOMIMETIC DOSAGES AND FORMULATIONS | Arbormentis LLC (US) | 2023-08-02 | — | — | EP | disclosed |