Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25053500 | 0.82 | PRKACA (0.35) | CSNK1DCSNK1EKCNH2PRKACAPRKACG | |
| SCHEMBL19142373 | 0.81 | SLC6A4 (0.42) | CSNK1DCSNK1EKCNH2HTR2CHTR2A | |
| SCHEMBL27885732 | 0.79 | PRKACA (0.36) | CSNK1DCSNK1EKCNH2PRKACAPRKACG | |
| Hydrochloric Acid SCHEMBL31444540 | 0.79 | HTR2C (0.39) | KDM1AKDM1BCSNK1DCSNK1EKCNH2 | |
| SCHEMBL280628 | 0.76 | CSNK1D (0.43) | KDM1ACSNK1DCSNK1EKCNH2PRKACA | |
| SCHEMBL8321907 | 0.76 | CSNK1D (0.43) | KDM1ACSNK1DCSNK1EKCNH2PRKACA | |
| SCHEMBL18387 | 0.76 | CSNK1D (0.43) | KDM1ACSNK1DCSNK1EKCNH2PRKACA | |
| SCHEMBL28286568 | 0.75 | KCNH2 (0.43) | KDM1AKDM1BKCNH2HTR2CHTR2A | |
| SCHEMBL7225260 | 0.75 | PRKACA (0.44) | KDM1ACSNK1DCSNK1EKCNH2HTR2C | |
| SCHEMBL25331969 | 0.75 | KDM1A (0.44) | KDM1AKDM1BCSNK1DCSNK1EKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551859-B | Aza condensed ring amide compound and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-08-27 | — | — | CN | disclosed |
| US-20230227460-A1 | FUSED AZA-HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227460-A1 | FUSED AZA-HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227460-A1 | FUSED AZA-HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD (CN) | 2023-07-20 | — | — | US | disclosed |
| WO-2023083362-A1 | DRUG FOR TREATING TUMORS | 石药集团中奇制药技术（石家庄）有限公司 | 2023-05-19 | — | — | WO | disclosed |
| CN-116115618-A | Medicine for treating tumor | 石药集团中奇制药技术（石家庄）有限公司 | 2023-05-16 | — | — | CN | disclosed |
| EP-4151635-A1 | FUSED AZA-HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2023-03-22 | — | — | EP | disclosed |
| CN-115551859-A | Aza condensed ring amide compound and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2022-12-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227460-A1 | FUSED AZA-HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | ROS1, ALK, ROR1 | KDM1A 559/4885KDM1B 1075/4885CSNK1D 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.