Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444529 | 0.84 | HTR2A (0.40) | SLC6A4HTR2AHTR2CHTR2BPRKACA | |
| SCHEMBL25907627 | 0.81 | KDM1A (0.41) | HTR2AHTR2CCSNK1DCSNK1EKCNH2 | |
| SCHEMBL20319860 | 0.78 | TAAR1 (0.38) | SLC6A4HTR2AHTR2CHTR2BOPRL1 | |
| SCHEMBL25316221 | 0.76 | MEN1 (0.44) | SLC6A4HTR2AHTR2CHTR2BKCNH2 | |
| Hydrochloric Acid SCHEMBL31444535 | 0.76 | HTR2A (0.39) | HTR2AHTR2CHTR2BOPRL1PRKACA | |
| SCHEMBL28519635 | 0.76 | MEN1 (0.44) | SLC6A4HTR2AHTR2CHTR2BKCNH2 | |
| SCHEMBL31444556 | 0.76 | PRKACA (0.36) | CSNK1DCSNK1EKCNH2OPRL1PRKACA | |
| SCHEMBL28785154 | 0.75 | PRKACA (0.52) | HTR2AHTR2CHTR2BCSNK1DCSNK1E | |
| SCHEMBL432870 | 0.75 | PRKACA (0.52) | HTR2AHTR2CHTR2BCSNK1DCSNK1E | |
| SCHEMBL31444311 | 0.75 | HTR2A (0.41) | SLC6A4HTR2AHTR2CHTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| US-11759760-B2 | Apparatus and process for the automated chemical synthesis of compounds | ETH ZURICH (CH) | 2023-09-19 | — | — | US | disclosed |
| US-11759760-B2 | Apparatus and process for the automated chemical synthesis of compounds | ETH ZURICH (CH) | 2023-09-19 | — | — | US | disclosed |
| US-20230072608-A1 | Apparatus and Process for the Automated Chemical Synthesis of Compounds | ETH ZURICH (CH) | 2023-03-09 | — | — | US | disclosed |
| US-20190209995-A1 | Apparatus and Process for the Automated Chemical Synthesis of Compounds | ETH ZURICH (CH) | 2019-07-11 | — | — | US | disclosed |
| WO-2018116285-A1 | SUBSTITUTED MORPHOLINE DERIVATIVES AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2018-06-28 | — | — | WO | disclosed |
| EP-3192583-A1 | APPARATUS AND PROCESS FOR THE AUTOMATED CHEMICAL SYNTHESIS OF COMPOUNDS | ETH Zurich (CH) | 2017-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209995-A1 | Apparatus and Process for the Automated Chemical Synthesis of Compounds | SQLE, FAH, ACACB | SLC6A4 3280/4885HTR2A 2911/4885HTR2C 1579/4885 |
| US-11759760-B2 | Apparatus and process for the automated chemical synthesis of compounds | SQLE, DCXR, FAH | SLC6A4 3332/4885HTR2A 3754/4885HTR2C 2477/4885 |
| US-20230072608-A1 | Apparatus and Process for the Automated Chemical Synthesis of Compounds | DCXR, SAMM50, AMD1 | SLC6A4 3165/4885HTR2A 2954/4885HTR2C 2111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.