Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25907367 | 0.78 | — | — | |
| SCHEMBL24192683 | 0.77 | POLB (0.43) | — | |
| SCHEMBL25907370 | 0.74 | MAPT (0.33) | MAPTCRHBPCRHR2 | |
| SCHEMBL6127869 | 0.72 | MAPT (0.41) | MAPTCRHBPCRHR2 | |
| SCHEMBL18539272 | 0.69 | MAPT (0.36) | MAPTCRHBPCRHR2 | |
| SCHEMBL24191913 | 0.69 | CYP3A4 (0.36) | MAPTCRHBPCRHR2 | |
| SCHEMBL22433007 | 0.68 | NQO2 (0.34) | MAPTCRHBPCRHR2 | |
| SCHEMBL6124139 | 0.68 | MAPT (0.36) | MAPTCRHBPCRHR2 | |
| SCHEMBL10136700 | 0.67 | GPR55 (0.31) | — | |
| SCHEMBL24192680 | 0.67 | POLB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708377-B2 | Analogues and derivatives of cephalotaxine and methods for making and using the compounds | OREGON STATE UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708377-B2 | Analogues and derivatives of cephalotaxine and methods for making and using the compounds | SLC6A2, NAPRT, SLC6A3 | MAPT 3705/4885CRHBP 2605/4885CRHR2 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.