⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24192696 | 0.83 | LMNA (0.39) | — | |
| SCHEMBL24192305 | 0.83 | LMNA (0.39) | — | |
| SCHEMBL24192872 | 0.83 | LMNA (0.39) | — | |
| SCHEMBL24192871 | 0.79 | KDM4E (0.32) | — | |
| SCHEMBL12712760 | 0.75 | KDM4E (0.46) | — | |
| SCHEMBL22442554 | 0.74 | — | — | |
| SCHEMBL24192880 | 0.71 | ADRB2 (0.35) | — | |
| SCHEMBL3099885 | 0.68 | — | — | |
| SCHEMBL27871249 | 0.67 | LMNA (0.42) | — | |
| SCHEMBL22019018 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708377-B2 | Analogues and derivatives of cephalotaxine and methods for making and using the compounds | OREGON STATE UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |