3-Hydroxybutyric Acid, (+/-)-

3-Hydroxybutyric Acid, (+/-)-

SCHEMBL2590789

CC(=O)OC(C)=O.CC(O)CC(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.42
ALOX15 P16050 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 2/20 0.38
MAPT P10636 1/20 0.37
GABRR1 P24046 2/20 0.36
FFAR3 O14843 1/20 0.35
TDP1 Q9NUW8 3/20 0.35
HSD17B10 Q99714 1/20 0.35
CACNA2D1 P54289 2/20 0.34
CACNB3 P54284 1/20 0.34
CACNA1C Q13936 1/20 0.34
PGR P06401 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
CACNA2D2 Q9NY47 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Hydroxybutyric Acid, (+/-)- SCHEMBL27749364 0.86 ALDH1A1 (0.48) ALDH1A1TSHRSLC22A6ALOX15SMN1; SMN2
3-Hydroxybutyric Acid, (+/-)- SCHEMBL29019982 0.85 SLC22A6 (0.50) ALDH1A1SLC22A6SMN1; SMN2LMNAMAPT
3-Hydroxybutyric Acid, (+/-)- SCHEMBL11263025 0.85 SLC22A6 (0.50) ALDH1A1SLC22A6ALOX15SMN1; SMN2LMNA
3-Hydroxybutyric Acid, (+/-)- SCHEMBL7654603 0.85 SLC22A6 (0.50) ALDH1A1SLC22A6SMN1; SMN2LMNAMAPT
(R)-3-Hydroxybutanoate SCHEMBL27669012 0.85 SLC22A6 (0.50) ALDH1A1SLC22A6ALOX15SMN1; SMN2LMNA
3-Hydroxybutyric Acid, (+/-)- SCHEMBL1897117 0.84 SLC22A6 (0.56) SLC22A6SMN1; SMN2LMNAMAPTGABRR1
3-Hydroxybutyric Acid, (+/-)- SCHEMBL1881926 0.84 SLC22A6 (0.56) SLC22A6SMN1; SMN2LMNAMAPTGABRR1
(R)-3-Hydroxybutanoate SCHEMBL29903959 0.84
(R)-3-Hydroxybutanoate SCHEMBL336331 0.84
(R)-3-Hydroxybutanoate SCHEMBL1533862 0.84 SLC22A6 (0.56) SLC22A6SMN1; SMN2LMNAMAPTGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111410302-A Method for denitrifying and recovering nitrogen from nitrifying biological floc aquaculture wastewater 上海海洋大学 2020-07-14 CN disclosed
EP-2563352-A1 FORMULATIONS OF QUINONES FOR THE TREATMENT OF OPHTHALMIC DISEASES Edison Pharmaceuticals, Inc. (US) 2013-03-06 EP disclosed
WO-2011137126-A1 FORMULATIONS OF QUINONES FOR THE TREATMENT OF OPHTHALMIC DISEASES EDISON PHARMACEUTICALS, INC. (US) 2011-11-03 WO disclosed