Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908199 | 0.81 | RECQL (0.44) | GRM5SMN1; SMN2RAB9ANPC1RECQL | |
| SCHEMBL25320721 | 0.78 | GPR35 (0.45) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL24367351 | 0.76 | PRMT5 (0.54) | GRM5SMN1; SMN2RAB9ANPC1RECQL | |
| SCHEMBL25786636 | 0.74 | PRMT5 (0.60) | GRM5SMN1; SMN2RAB9ANPC1RECQL | |
| SCHEMBL24691381 | 0.74 | GRM5 (0.48) | GRM5SMN1; SMN2RAB9ANPC1RECQL | |
| SCHEMBL24365834 | 0.73 | GRM5 (0.43) | GRM5SMN1; SMN2RECQLALDH1A1HPGD | |
| SCHEMBL25955896 | 0.71 | PRMT5 (0.46) | GRM5SMN1; SMN2RAB9ARECQLALDH1A1 | |
| SCHEMBL24366708 | 0.71 | PRMT5 (0.46) | GRM5SMN1; SMN2RAB9ARECQLALDH1A1 | |
| SCHEMBL25908271 | 0.71 | GRM5 (0.40) | GRM5SMN1; SMN2RECQLL3MBTL1EPHX2 | |
| SCHEMBL24365211 | 0.70 | PRMT5 (0.60) | GRM5RECQLPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |