Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908271 | 0.90 | GRM5 (0.40) | GRM5RECQLALDH1A1HPGDPRMT5 | |
| SCHEMBL25321038 | 0.78 | PARP1 (0.36) | GRM5 | |
| SCHEMBL25322726 | 0.77 | PARP1 (0.35) | GRM5 | |
| SCHEMBL24367351 | 0.76 | PRMT5 (0.54) | GRM5RECQLALDH1A1PRMT5POLB | |
| SCHEMBL25786636 | 0.74 | PRMT5 (0.60) | GRM5RECQLALDH1A1PRMT5POLB | |
| SCHEMBL25955903 | 0.74 | GRM5 (0.39) | GRM5RECQLALDH1A1HPGDPRMT5 | |
| SCHEMBL24691381 | 0.74 | GRM5 (0.48) | GRM5RECQLALDH1A1PRMT5POLB | |
| SCHEMBL24366708 | 0.73 | PRMT5 (0.46) | GRM5RECQLALDH1A1PRMT5POLB | |
| SCHEMBL24365834 | 0.73 | GRM5 (0.43) | GRM5RECQLALDH1A1HPGDPRMT5 | |
| SCHEMBL25955896 | 0.73 | PRMT5 (0.46) | GRM5RECQLALDH1A1PRMT5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |