Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.49 |
| ▸ | TNF | P01375 | 7/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25901729 | 0.87 | TIPARP (0.54) | TIPARPTNF | |
| SCHEMBL25898605 | 0.84 | TIPARP (0.49) | TIPARPTNFGRM2 | |
| SCHEMBL25908010 | 0.82 | TIPARP (0.65) | TIPARPTNF | |
| SCHEMBL25898391 | 0.78 | TIPARP (0.46) | TIPARPTNFGRM2 | |
| SCHEMBL25908307 | 0.78 | BRD9 (0.38) | TIPARP | |
| SCHEMBL26785815 | 0.77 | TNF (0.43) | TIPARPTNFGRM2PSMB5CNR2 | |
| SCHEMBL25902196 | 0.76 | TIPARP (0.46) | TIPARPTNF | |
| SCHEMBL25898542 | 0.76 | TIPARP (0.48) | TIPARPTNFGRM2CNR2 | |
| SCHEMBL25907205 | 0.76 | TIPARP (0.47) | TIPARPTNFGRM2 | |
| SCHEMBL25897832 | 0.75 | TIPARP (0.49) | TIPARPTNFGRM2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |