Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.65 |
| ▸ | FLT3 | P36888 | 4/20 | 0.34 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26787748 | 0.89 | TIPARP (0.59) | TIPARPFLT3KITCHEK1TNF | |
| SCHEMBL25899853 | 0.88 | TIPARP (0.60) | TIPARPFLT3KITCHEK1TNF | |
| SCHEMBL25901729 | 0.87 | TIPARP (0.54) | TIPARPTNF | |
| SCHEMBL25900854 | 0.84 | TIPARP (0.56) | TIPARPFLT3KITCHEK1 | |
| SCHEMBL25900139 | 0.83 | TIPARP (0.56) | TIPARPFLT3KITCHEK1 | |
| SCHEMBL25908352 | 0.82 | TIPARP (0.49) | TIPARPTNF | |
| SCHEMBL25321465 | 0.81 | TIPARP (0.90) | TIPARP | |
| SCHEMBL30550824 | 0.81 | TIPARP (0.90) | TIPARP | |
| SCHEMBL25321469 | 0.81 | TIPARP (0.90) | TIPARP | |
| SCHEMBL25900208 | 0.80 | TIPARP (0.54) | TIPARPFLT3KITCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |