Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 16/20 | 0.44 |
| ▸ | MAP3K13 | O43283 | 2/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908430 | 1.00 | MAP3K12 (0.44) | MAP3K12MAP3K13PIK3R1PIK3CASYK | |
| SCHEMBL25908431 | 0.77 | PIK3CA (0.42) | MAP3K12PIK3CA | |
| SCHEMBL25908367 | 0.77 | PIK3CA (0.36) | MAP3K12PIK3R1PIK3CA | |
| SCHEMBL25908374 | 0.71 | KCNN3 (0.35) | — | |
| SCHEMBL25908373 | 0.70 | PDE10A (0.51) | — | |
| SCHEMBL25908694 | 0.69 | MAP3K7 (0.45) | MAP3K12MAP3K13PIK3R1PIK3CA | |
| SCHEMBL31674973 | 0.66 | MAP3K12 (0.55) | MAP3K12MAP3K13PIK3R1PIK3CA | |
| SCHEMBL16224347 | 0.66 | MAP3K12 (0.55) | MAP3K12MAP3K13PIK3R1PIK3CA | |
| SCHEMBL18307182 | 0.64 | MAP3K12 (0.48) | MAP3K12MAP3K13 | |
| SCHEMBL18307132 | 0.64 | MAP3K12 (0.48) | MAP3K12MAP3K13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138343-A1 | NEW TYPE PYRAZOLOPYRIMIDINE COMPOUND AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚尧生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |