Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 2/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 13/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.36 |
| ▸ | DLK1 | P80370 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908696 | 0.82 | MAP3K7 (0.44) | MAP3K7PIK3R1PIK3CAMAP3K12DLK1 | |
| SCHEMBL25908487 | 0.79 | CCNT1 (0.38) | LRRK2ATR | |
| SCHEMBL25160195 | 0.79 | ATR (0.53) | ATR | |
| SCHEMBL25908450 | 0.78 | MAP3K7 (0.43) | MAP3K7LRRK2 | |
| SCHEMBL25908698 | 0.76 | ATR (0.45) | MAP3K7PIK3R1PIK3CAATR | |
| SCHEMBL25908309 | 0.72 | PDE10A (0.49) | — | |
| SCHEMBL25908428 | 0.69 | MAP3K12 (0.44) | PIK3R1PIK3CAMAP3K12MAP3K13 | |
| SCHEMBL25908430 | 0.69 | MAP3K12 (0.44) | PIK3R1PIK3CAMAP3K12MAP3K13 | |
| SCHEMBL30705231 | 0.67 | MAP3K12 (0.43) | MAP3K12LRRK2MAP3K13DLK1 | |
| SCHEMBL29768061 | 0.67 | MAP3K12 (0.43) | MAP3K12LRRK2MAP3K13DLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4467545-A1 | NEW TYPE PYRAZOLOPYRIMIDINE COMPOUND AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Yayo Biotechnology Co. Ltd (CN) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023138343-A1 | NEW TYPE PYRAZOLOPYRIMIDINE COMPOUND AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚尧生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |
| WO-2023138343-A1 | NEW TYPE PYRAZOLOPYRIMIDINE COMPOUND AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚尧生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |