Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934135 | 0.78 | NOS3 (0.53) | UHRF1NOS3NOS1NOS2CYP1A2 | |
| SCHEMBL28198255 | 0.78 | UHRF1 (0.50) | UHRF1NOS3NOS1NOS2CYP1A2 | |
| SCHEMBL24914702 | 0.76 | UHRF1 (0.39) | UHRF1NOS3NOS1NOS2NUDT1 | |
| SCHEMBL10330646 | 0.76 | UHRF1 (0.48) | UHRF1NOS3NOS1NOS2CYP1A2 | |
| SCHEMBL22403923 | 0.72 | UHRF1 (0.31) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL7723010 | 0.70 | UHRF1 (0.42) | UHRF1NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL22402382 | 0.69 | UHRF1 (0.50) | UHRF1NOS3NOS1NOS2NUDT1 | |
| SCHEMBL2088616 | 0.69 | — | — | |
| SCHEMBL30014401 | 0.69 | — | — | |
| SCHEMBL29198060 | 0.69 | UHRF1 (0.41) | UHRF1NOS3NOS1NOS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219488-A1 | METHOD FOR THE PREPARATION OF UREA COMPOUNDS AS SMARCA2/BRM-ATPASE INHIBITORS | Novartis AG (CH) | 2023-08-02 | — | — | EP | disclosed |