Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25316213 | 0.90 | HTR1A (0.41) | GPR119DRD2SLC6A4ADRA1DADRA1A | |
| SCHEMBL30506845 | 0.90 | HTR1A (0.41) | GPR119DRD2SLC6A4ADRA1DADRA1A | |
| SCHEMBL25932861 | 0.89 | KDM4E (0.41) | HTR1AHTR2AHTR7HTR6DRD3 | |
| SCHEMBL25933785 | 0.89 | MAOA (0.35) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL30507496 | 0.88 | ALK (0.42) | GPR119DRD2SLC6A4ADRA1DADRA1A | |
| SCHEMBL25317462 | 0.88 | ALK (0.42) | GPR119DRD2SLC6A4ADRA1DADRA1A | |
| SCHEMBL25317378 | 0.86 | HRH3 (0.44) | GPR119DRD2DRD3 | |
| SCHEMBL25932252 | 0.83 | HTR1A (0.37) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL25315565 | 0.82 | HTR1A (0.41) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL30507406 | 0.82 | HTR1A (0.41) | DRD2HTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |