Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.49 |
| ▸ | KCNN3 | Q9UGI6 | 14/20 | 0.43 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.41 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908487 | 0.75 | CCNT1 (0.38) | PDE10ACCNT1CDK9 | |
| SCHEMBL25908450 | 0.74 | MAP3K7 (0.43) | PDE10ACCNT1CDK9 | |
| SCHEMBL25160195 | 0.73 | ATR (0.53) | CHEK1 | |
| SCHEMBL25908694 | 0.72 | MAP3K7 (0.45) | — | |
| SCHEMBL29344715 | 0.71 | PDE10A (0.67) | PDE10AKCNN3KCNN1KCNN2CCNT1 | |
| SCHEMBL22855162 | 0.71 | PDE10A (0.57) | PDE10AKCNN3KCNN1KCNN2 | |
| SCHEMBL11467425 | 0.69 | PDE10A (0.59) | PDE10AKCNN3KCNN1KCNN2 | |
| SCHEMBL30974 | 0.68 | PDE10A (0.67) | PDE10AKCNN3KCNN1KCNN2CHEK1 | |
| SCHEMBL14158199 | 0.67 | PDE10A (0.61) | PDE10AKCNN3KCNN1KCNN2CCNT1 | |
| SCHEMBL29869 | 0.67 | PDE10A (1.00) | PDE10AKCNN3KCNN1KCNN2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138343-A1 | NEW TYPE PYRAZOLOPYRIMIDINE COMPOUND AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚尧生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |