Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 8/20 | 0.38 |
| ▸ | MET | P08581 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 7/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR6 | P50406 | 5/20 | 0.36 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.35 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30507055 | 0.91 | MET (0.41) | IP6K1METHTR7HTR1AHTR2A | |
| SCHEMBL30507382 | 0.91 | MET (0.41) | IP6K1METHTR7HTR1AHTR2A | |
| SCHEMBL30507077 | 0.91 | MET (0.41) | IP6K1METHTR7HTR1AHTR2A | |
| SCHEMBL25316933 | 0.91 | MET (0.41) | IP6K1METHTR7HTR1AHTR2A | |
| SCHEMBL25315813 | 0.91 | MET (0.41) | IP6K1METHTR7HTR1AHTR2A | |
| SCHEMBL25315817 | 0.91 | MET (0.41) | IP6K1METHTR7HTR1AHTR2A | |
| SCHEMBL25318634 | 0.83 | HTR7 (0.42) | IP6K1METHTR7HTR1AHTR2A | |
| SCHEMBL30507195 | 0.83 | HTR7 (0.42) | IP6K1METHTR7HTR1AHTR2A | |
| SCHEMBL25315963 | 0.81 | HTR7 (0.42) | IP6K1METHTR7HTR1AHTR2A | |
| SCHEMBL25316738 | 0.81 | HTR7 (0.42) | IP6K1METHTR7HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |