Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823055 | 0.79 | MTNR1A (0.61) | GRIN2BMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL4606877 | 0.79 | MTNR1A (0.61) | GRIN2BMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL459537 | 0.79 | GRIN2B (0.65) | GRIN2BMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL7838746 | 0.79 | MTNR1A (0.61) | GRIN2BMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL26515641 | 0.79 | GRIN2B (0.56) | GRIN2BMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL29599386 | 0.79 | MTNR1A (0.61) | GRIN2BMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL823057 | 0.79 | MTNR1A (0.61) | GRIN2BMTNR1AMTNR1BCA1CA2 | |
| Hydrochloric Acid SCHEMBL7430755 | 0.78 | MTNR1A (0.59) | GRIN2BMTNR1AMTNR1BCA1CA2 | |
| Bromide SCHEMBL7336860 | 0.78 | MTNR1A (0.59) | GRIN2BMTNR1AMTNR1BCA1CA2 | |
| Hydrochloric Acid SCHEMBL1026136 | 0.78 | MTNR1A (0.59) | GRIN2BMTNR1AMTNR1BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218818-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | Kyoto University (JP) | 2023-08-02 | — | — | EP | disclosed |