Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25905434 | 0.79 | CYP2D6 (0.41) | SCN1ASCN2ASCN3ACYP2D6ADRA2A | |
| SCHEMBL21138993 | 0.77 | CYP2D6 (0.42) | SCN1ASCN2ASCN3ACYP2D6ADRA2A | |
| SCHEMBL17988494 | 0.75 | CA1 (0.47) | SCN1ASCN2ASCN3ACYP2D6ADRA2A | |
| SCHEMBL10304814 | 0.72 | CYP2D6 (0.50) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL13784396 | 0.70 | AR (0.43) | CYP2D6CYP1A2CYP2A6P2RX3P2RX2 | |
| SCHEMBL2737299 | 0.69 | CYP2D6 (0.47) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL487152 | 0.69 | CYP2D6 (0.67) | SCN1ASCN2ASCN3ACYP2D6ADRA2A | |
| SCHEMBL1494189 | 0.67 | CYP2D6 (0.46) | SCN1ASCN2ASCN3ACYP2D6ADRA2A | |
| SCHEMBL19363996 | 0.67 | CYP2D6 (0.46) | SCN1ASCN2ASCN3ACYP2D6ADRA2A | |
| SCHEMBL8802746 | 0.67 | ALDH1A1 (0.53) | CYP2D6ADRA2AADRA1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242552-A1 | Nitrogen-Containing Heterocyclic Compound, Preparation Method Therefor and Use Thereof | 280 Bio, Inc (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242552-A1 | Nitrogen-Containing Heterocyclic Compound, Preparation Method Therefor and Use Thereof | NRAS, KRAS, RAB8A | SCN1A 1194/4885SCN2A 2909/4885SCN3A 1992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.