Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 1/20 | 0.54 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19122052 | 0.86 | CYP2D6 (0.51) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL7524532 | 0.85 | CYP2D6 (0.65) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL5418590 | 0.84 | CYP2D6 (0.50) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL31357463 | 0.84 | CYP2D6 (0.50) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL6432485 | 0.84 | CYP2D6 (0.50) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL8223272 | 0.84 | THRB (0.51) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL11260013 | 0.83 | CYP2D6 (0.62) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL2498221 | 0.83 | ADRA1A (0.74) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL9027223 | 0.83 | CYP2D6 (0.62) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL9027230 | 0.83 | ADRA1A (0.69) | CYP2D6ADRA2AADRA1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744243-B | (E)-2-phenyl-3-(3,5-dimethoxy-4 '-isopropyl benzene) purification method of propenoic acid | HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-06 | — | — | CN | claimed |
| US-4473713-A | Hydrolysis of aryl-aliphatic ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-25 | — | — | US | claimed |
| US-11845715-B2 | — | — | 2023-12-19 | — | — | US | disclosed |
| US-20230233560-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230233560-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230159537-A1 | COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF IN PREPARATION OF ANTI-CANCER DRUG | TIANJIN JIKUN MEDICAL TECHNOLOGY CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159537-A1 | COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF IN PREPARATION OF ANTI-CANCER DRUG | TIANJIN JIKUN MEDICAL TECHNOLOGY CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230124361-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-04-20 | — | — | US | disclosed |
| US-20230043959-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE CORPORATION | 2023-02-09 | — | — | US | disclosed |
| US-11505528-B2 | Inhibitors of microbially induced amyloid | AXIAL THERAPEUTICS, INC. (US) | 2022-11-22 | — | — | US | disclosed |
| US-20220213108-A1 | DEAZAGUAINE COMPOUNDS AS JAK2 V617F INHIBITORS | INCYTE CORPORATION | 2022-07-07 | — | — | US | disclosed |
| US-20060029811-A1 | mixing a phenolic compound containing the inorganic microfine particle(SiO2) and a compound containing at least one of the glycidyl group and/or an epoxy group containing the inorganic microfine particle; fireproofing; good mechanical properties; heat resistance; automobiles, construction, electronics | NIPPON SHOKUBAI CO., LTD. (JP) | 2006-02-09 | — | — | US | disclosed |
| CN-1656177-A | Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica | NIPPON CATALYTIC CHEM IND (JP) | 2005-08-17 | — | — | CN | disclosed |
| US-6858304-B2 | Preparation of polyindanebisphenols and polymers derived therefrom | HONEYWELL INTERNATIONAL INC. (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030069384-A1 | Preparation of polyindanebisphenols and polymers derived therefrom | HONEYWELL INTERNATIONAL INC. | 2003-04-10 | — | — | US | disclosed |
| EP-0882029-B1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6509063-B1 | Copolymerization with such as epoxy resin, epoxy function-alized elastomer or amorphous polycarbonate; impregnating monomer solution on fibrous support and desolvating to form dry laminate | HONEYWELL INTERNATIONAL INC. | 2003-01-21 | — | — | US | disclosed |
| US-6153721-A | CRACKING BISPHENOL A TO PRODUCE A MIXTURE COMPRISING P-ISOPROPENYLPHENOL AND PHENOL, COPOLYMERIZING THE RESULTING MIXTURE WITH AN ISOPROPENYLBENZENE COMPOUND IN A SUITABLE POLYMERIZATION MEDIUM TO YIELD A POLYINDANEBISPHENOL. | HONEYWELL INTERNATIONAL INC. (US) | 2000-11-28 | — | — | US | disclosed |
| US-6090836-A | DIETETICS; ADJUSTMENT OF TRIGLYCERIDE CONCENTRATION | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-4473713-A | Hydrolysis of aryl-aliphatic ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11505528-B2 | Inhibitors of microbially induced amyloid | SNCA, PARK7, PRNP | CYP2D6 4352/4885ADRA2A 2603/4885ADRA1A 2801/4885 |
| US-11845715-B2 | — | NLRP3, PYCARD, NOD1 | CYP2D6 4325/4885ADRA2A 4471/4885ADRA1A 4437/4885 |
| US-20230159537-A1 | COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF IN PREPARATION OF ANTI-CANCER DRUG | FGFR1, FGFR3, FGFR4 | CYP2D6 1725/4885ADRA2A 4714/4885ADRA1A 4355/4885 |
| US-20220213108-A1 | DEAZAGUAINE COMPOUNDS AS JAK2 V617F INHIBITORS | JAK2, JAK1, VHL | CYP2D6 2635/4885ADRA2A 4321/4885ADRA1A 4629/4885 |
| US-20230124361-A1 | SMALL MOLECULE STING ANTAGONISTS | STING1, CGAS, MAVS | CYP2D6 4865/4885ADRA2A 2232/4885ADRA1A 2383/4885 |
| US-20230233560-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | CYP2D6 3373/4885ADRA2A 649/4885ADRA1A 620/4885 |
| US-20230043959-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | JAK1, JAK2, JAK3 | CYP2D6 3436/4885ADRA2A 2608/4885ADRA1A 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.