SCHEMBL25909623

SCHEMBL25909623

Clc1cccc(CC[SiH](c2ccccc2)c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.52
SIGMAR1 Q99720 1/20 0.46
PNMT P11086 1/20 0.46
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
AOC3 Q16853 1/20 0.45
HTR3E A5X5Y0 1/20 0.45
HTR3B O95264 1/20 0.45
HTR3A P46098 1/20 0.45
HTR3D Q70Z44 1/20 0.45
HTR3C Q8WXA8 1/20 0.45
IDO1 P14902 2/20 0.44
TDO2 P48775 1/20 0.44
C3AR1 Q16581 1/20 0.44
P2RX7 Q99572 1/20 0.43
PLAAT3 P53816 2/20 0.42
PLAAT5 Q96KN8 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25909608 0.80 ALDH1A1 (0.46) TAAR1SIGMAR1ALDH1A1HPGDSMN1; SMN2
SCHEMBL25909624 0.79 TAAR1 (0.43) TAAR1SIGMAR1MEN1KMT2AAOC3
SCHEMBL25909606 0.79 TAAR1 (0.52) TAAR1ALDH1A1IDO1
SCHEMBL28907495 0.79 TAAR1 (0.52) TAAR1SIGMAR1SMN1; SMN2IDO1AGXT
SCHEMBL25909617 0.79 TAAR1 (0.52) TAAR1IDO1AGXT
SCHEMBL23071686 0.78 TAAR1 (0.65) TAAR1SIGMAR1PNMTMEN1ALDH1A1
SCHEMBL12050856 0.76 TAAR1 (0.74) TAAR1PNMTAOC3HTR3EHTR3B
SCHEMBL12040536 0.73 TAAR1 (0.59) TAAR1SIGMAR1PNMTMEN1ALDH1A1
SCHEMBL28532243 0.73 CYP1A2 (0.52) SIGMAR1KMT2A
SCHEMBL17937604 0.72 TAAR1 (0.49) TAAR1PNMTAOC3HTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241597-A1 PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS TEXAS TECH UNIVERSITY SYSTEM 2023-08-03 US disclosed