SCHEMBL25909658

SCHEMBL25909658

CC(c1ccccc1)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.41
KDM4E B2RXH2 2/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
CYP2D6 P10635 1/20 0.39
LMNA P02545 1/20 0.39
HIF1A Q16665 1/20 0.39
ALDH1A1 P00352 2/20 0.38
DPP4 P27487 2/20 0.38
ALOX5 P09917 1/20 0.38
F2 P00734 1/20 0.38
TSHR P16473 1/20 0.38
MIF P14174 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25909657 1.00 TAAR1 (0.41) TAAR1KDM4EADRA2AADRA2CCYP2D6
SCHEMBL28533683 0.84 HTR2A (0.44) ADRA2ACYP2D6LMNAHIF1AALDH1A1
SCHEMBL28399569 0.84 ALDH1A1 (0.39) KDM4ECYP2D6LMNAALDH1A1
SCHEMBL28399566 0.84 ALDH1A1 (0.39) KDM4ECYP2D6LMNAALDH1A1
SCHEMBL28471422 0.84 ALDH1A1 (0.39) KDM4ECYP2D6LMNAALDH1A1
SCHEMBL28524565 0.81 ACP3 (0.46) TAAR1LMNATSHR
SCHEMBL28479411 0.81 TP53 (0.48) TAAR1KDM4ELMNAALDH1A1TSHR
SCHEMBL28405384 0.81 CA4 (0.48) ALDH1A1TSHR
SCHEMBL28481733 0.81 CA4 (0.48) ALDH1A1TSHR
SCHEMBL28479410 0.81 TP53 (0.48) TAAR1KDM4ELMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241597-A1 PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS TEXAS TECH UNIVERSITY SYSTEM 2023-08-03 US disclosed