SCHEMBL28524565

SCHEMBL28524565

Cc1cccc(C(C)[SiH](c2ccccc2)c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.46
EPHX1 P07099 1/20 0.41
ACHE P22303 2/20 0.41
NPSR1 Q6W5P4 1/20 0.38
OPRM1 P35372 2/20 0.37
OPRD1 P41143 2/20 0.37
OPRK1 P41145 2/20 0.37
OPRL1 P41146 2/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
ALOX12 P18054 1/20 0.37
MAPT P10636 1/20 0.37
AOC3 Q16853 1/20 0.36
CYP19A1 P11511 2/20 0.36
GPR139 Q6DWJ6 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
TACR1 P25103 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28479285 0.79 IDO1 (0.46) EPHX1ACHEAOC3
SCHEMBL28907496 0.79 IDO1 (0.46)
SCHEMBL28479284 0.79 IDO1 (0.46) EPHX1ACHEAOC3
SCHEMBL9812362 0.75 ACP3 (0.52) ACP3EPHX1ACHENPSR1OPRM1
Isopropylbenzene SCHEMBL22653317 0.75 ACP3 (0.52) ACP3EPHX1ACHENPSR1OPRM1
SCHEMBL28054154 0.75 ACP3 (0.52) ACP3EPHX1ACHENPSR1OPRM1
SCHEMBL30080262 0.75 IDO1 (0.50) ACP3EPHX1OPRM1OPRD1OPRK1
SCHEMBL9284625 0.74 ACHE (0.52) ACP3EPHX1ACHENPSR1MAPT
SCHEMBL28401416 0.74 ALDH1A1 (0.47)
SCHEMBL30080127 0.74 ALDH1A1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112387313-A Tridentate phenanthroline manganese catalyst and application thereof in synthesis of organic silicon/boron compound 中山大学 2021-02-23 CN disclosed