Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 2/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24051978 | 0.85 | EGFR (0.47) | EGFRAPPMAPTSNCAMEN1 | |
| SCHEMBL17448067 | 0.77 | CYP11B1 (0.41) | EGFRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL12653740 | 0.75 | CYP1A2 (0.48) | MAPTMEN1POLBKMT2ACYP1A2 | |
| SCHEMBL17918989 | 0.73 | EGFR (0.55) | EGFRAPPMAPTSNCAMEN1 | |
| SCHEMBL16845655 | 0.72 | CA12 (0.47) | MEN1KMT2A | |
| SCHEMBL12366193 | 0.71 | CYP1A2 (0.59) | EGFRMEN1NPC1POLBCASP6 | |
| SCHEMBL18003378 | 0.71 | KDM4E (0.50) | EGFRMEN1NPC1POLBKMT2A | |
| SCHEMBL19359062 | 0.69 | ALDH1A1 (0.48) | MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13415 | 0.69 | BACE1 (0.44) | MAPTMEN1PABPC1KMT2ACYP1A2 | |
| SCHEMBL16523329 | 0.69 | BACE1 (0.44) | MAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |