Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 7/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910810 | 0.92 | CSF1R (0.44) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25910709 | 0.90 | CSF1R (0.42) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25910796 | 0.89 | CSF1R (0.52) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25909920 | 0.88 | CSF1R (0.45) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25909925 | 0.87 | CSF1R (0.44) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25910794 | 0.86 | CSF1R (0.61) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25910705 | 0.84 | CSF1R (0.47) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25911894 | 0.83 | CSF1R (0.51) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25910706 | 0.83 | CSF1R (0.46) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25910037 | 0.83 | CSF1R (0.50) | CSF1RPDGFRBPDGFRALCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |