Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 13/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.61 |
| ▸ | FLT3 | P36888 | 5/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | KIT | P10721 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25909794 | 0.89 | CSF1R (0.75) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25909900 | 0.86 | CSF1R (0.54) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25911894 | 0.85 | CSF1R (0.51) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910156 | 0.85 | CSF1R (0.74) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25909923 | 0.84 | CSF1R (0.76) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910037 | 0.84 | CSF1R (0.50) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910705 | 0.82 | CSF1R (0.47) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910925 | 0.81 | CSF1R (0.47) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25913293 | 0.81 | CSF1R (0.52) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25911790 | 0.80 | CSF1R (0.53) | CSF1RPDGFRAFLT3PDGFRBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |