Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 12/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.57 |
| ▸ | FLT3 | P36888 | 4/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | KIT | P10721 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25909794 | 0.87 | CSF1R (0.75) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910683 | 0.85 | CSF1R (0.56) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25911790 | 0.84 | CSF1R (0.53) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910028 | 0.84 | CSF1R (0.53) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910568 | 0.84 | CSF1R (0.55) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910021 | 0.84 | CSF1R (0.62) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25913293 | 0.84 | CSF1R (0.52) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25909920 | 0.83 | CSF1R (0.45) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910302 | 0.83 | CSF1R (0.51) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25912060 | 0.82 | CSF1R (0.51) | CSF1RPDGFRAFLT3PDGFRBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |