Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055978 | 0.89 | GRM1 (0.40) | GRM1SLC6A12SLC6A11 | |
| SCHEMBL27547000 | 0.82 | MAPT (0.31) | — | |
| SCHEMBL23880338 | 0.75 | LMNA (0.39) | — | |
| SCHEMBL23880337 | 0.75 | LMNA (0.39) | — | |
| SCHEMBL23880339 | 0.75 | LMNA (0.39) | — | |
| SCHEMBL5522614 | 0.73 | GRM1 (0.42) | GRM1SLC6A12SLC6A11 | |
| SCHEMBL25910070 | 0.73 | GRM1 (0.42) | GRM1SLC6A12SLC6A11 | |
| SCHEMBL5595209 | 0.71 | GRM1 (0.33) | GRM1 | |
| SCHEMBL28486688 | 0.69 | HSD11B1 (0.30) | — | |
| Urea SCHEMBL28062092 | 0.65 | TDP1 (0.50) | GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142619-B | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112142619-A | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2020-12-29 | — | — | CN | disclosed |