Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 7/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.37 |
| ▸ | FLT3 | P36888 | 4/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 7/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910558 | 0.85 | CSF1R (0.55) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL25910554 | 0.85 | CSF1R (0.37) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL25910285 | 0.85 | PDGFRB (0.45) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL25910691 | 0.84 | CSF1R (0.38) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL25910414 | 0.84 | PDGFRB (0.45) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL25910282 | 0.83 | TLR7 (0.34) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25912711 | 0.83 | RAF1 (0.35) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL25910028 | 0.83 | CSF1R (0.53) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL25910828 | 0.81 | BRAF (0.45) | CSF1RPDGFRAPDGFRBKDRLCK | |
| SCHEMBL25913125 | 0.80 | KCNH2 (0.41) | KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |