Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910282 | 0.91 | TLR7 (0.34) | CSF1RPDGFRBKCNH2HRH3LCK | |
| SCHEMBL25910179 | 0.83 | CSF1R (0.37) | CSF1RPDGFRBKCNH2HRH3LCK | |
| SCHEMBL25911492 | 0.82 | TLR7 (0.34) | CSF1RPDGFRBKCNH2HRH3LCK | |
| SCHEMBL25911473 | 0.79 | CSF1R (0.48) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL25909902 | 0.79 | CSF1R (0.48) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL25910174 | 0.78 | ADORA2A (0.44) | BRAFCSF1RPDGFRBPDGFRA | |
| SCHEMBL25910294 | 0.77 | CSF1R (0.55) | RAF1BRAFCSF1RPDGFRBLCK | |
| SCHEMBL25910288 | 0.76 | CSF1R (0.41) | RAF1BRAFCSF1RPDGFRBLCK | |
| SCHEMBL25910028 | 0.75 | CSF1R (0.53) | RAF1BRAFCSF1RPDGFRBLCK | |
| SCHEMBL25911490 | 0.75 | KCNH2 (0.37) | KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |